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SECOND INTERNATIONAL MASTERCLASS IN ANDROLOGY AND IVF

Featuring Expert Presentations by:

International Experts from the Global Andrology Forum

G. M. Colpi

G.-M. Pinggera

S. Cayan

MD

C. Wyns

O. Sefrioui

N. Louanjli

A. Bensouda

I. Ziouziou

I. Maldonado

C. Konstantinidis

A. Ryzhkov

A. Rambhatla

R. Shah

A. Agarwal

december 3-6, 2025, AGADIR, MOROCCO

Learning Objectives:

Overall Goal:
To enhance the multidisciplinary clinical and surgical competencies of healthcare profes- sionals involved in male infertility and IVF through a case-based, hands-on, and evidence-based approach led by international experts.

After attending this masterclass, participants will be able to:

1. Improve knowledge and diagnostic capabilities in male infertility:
Understand the implications of updated semen analysis guidelines (WHO 6th Edition) on clinical practice.
Evaluate the role of sperm DNA fragmentation and genetic testing in non-obstructive azoospermia.
Gain insights into the integration of AI in sperm assessment.

2. Optimize case-based clinical decision-making:
Approach complex infertility scenarios such as recurrent pregnancy loss, varicocele management, and hormonal therapy in azoospermia.
Engage in expert-led discussions on controversial and evidence-sensitive topics.

3. Enhance microsurgical and laboratory technical skills:
Acquire hands-on microsurgical techniques relevant to varicocelectomy, vaso-epididymal anastomosis, and micro-TESE.
Learn tissue processing and sperm retrieval techniques from real laboratory case videos.

4. Collaborate in multidisciplinary fertility management:
Coordinate male and female treatment protocols for couples with infertility.
Integrate andrology, gynecology, and embryology approaches in ART cycles.

5. Apply the latest international guidelines in daily practice:
Understand and implement the 2025 GAF Guidelines on varicocele, SDF, NOA, and premature ejaculation.
Evaluate recent advances in male sexual dysfunction management including regenerative therapies and penile implants.

DAY 1 - DECEMBER 3, 2025

  • 08:30 - 13:00: Group 1
  • 14:00 - 18:30: Group 2
  • Ergonomics in microsurgery
  • Microsurgical dissection
  • Microsurgical sutures
  • MicroTESE on animal model
  • Handling the extracted tubules by the embryologist
  • HANDS-ON TRAINING FACULTY
  • Microsurgery:
  • G. Colpi
  • G.-M. Pinggera
  • M. Fakiri
  • A. Ryzhkov
  • I. Ziouziou
  • H. Dergamoun
  • Embryology:
  • E. Piatti
  • 18:00 - 19:00: E-POSTER PRESENTATIONS & ORAL COMMUNICATIONS

DAY 2 - DECEMBER 4, 2025

  • 08:30 - 18:00: LIVE SURGERY – 2 CASES OF MTESE
  • Moderators: G.-M. Pinggera, Z. Abouelfadel
  • Professor G. Colpi has been performing microTESE for the past 26 years.
  • Over the years, he has shared his expertise with surgeons worldwide, trained numerous colleagues in this technique, and is widely recognized as a leading expert in microTESE surgery.
  • G. M. Colpi

DAY 3 - DECEMBER 5, 2025

  • 08:30 - 09:00: Opening Session: Registration & Welcome
  • 09:00 - 09:25: Welcome Speech:
  • President of the organization committee I. Ziouziou
  • Dean of the School of Medicine and Pharmacy of Agadir Pr. M. Soufi
  • General Director of the Souss Massa University Hospital Pr. M. Arrayhani
  • 09:25 - 09:40: Introduction to the Masterclass. A. Agarwal
  • 09:40 - 10:45: Laboratory tests for male infertility, and their clinical implications
  • Moderator: G. Colpi
  • Co-moderator: I. Maldonado
  • 09:40 - 09:55: The impact of WHO-2021 (6th ed.) semen analysis manual on infertility treatment planning. A. Rambhatla
  • 09:55 - 10:10: Update on the evaluation of sperm DNA damage and its impact on fertility outcomes. A. Agarwal
  • 10:10 - 10:25: Genetic insight into non-obstructive azoospermia: Testing and its clinical implications. I. Ziouziou
  • 10:25 - 10:40: Use of AI-based semen analyzers and image analysis to identify testicular sperm. G.-M. Pinggera
  • 10:40 - 11:00: Discussion on “Laboratory tests and clinical use in infertility”
  • 11:00 - 11:30: COFFEE BREAK
  • 11:30 - 13:00: Management of difficult cases in male infertility
  • Moderators: A. Ryzhkov, A. Rambathla, Y. Ait Benkaddour
  • 11:30 - 12:00: Case 1. Approach to recurrent pregnancy loss
  • Case presenter: C. Wyns
  • Andrologist: Do male factors truly contribute to recurrent pregnancy loss? G.-M. Pinggera
  • Gynecologist: Maternal-related reasons for recurrent pregnancy loss. O. Sefrioui
  • Take-home messages: C. Wyns
  • 12:00 - 12:30: Case 2. The varicocele conundrum
  • Case presenter: S. Cayan
  • Andrologist: Does varicocele repair improve semen parameters significantly? I. Ziouziou
  • Gynecologist: Can varicocele repair prior to ART improve outcomes after ICSI? C. Wyns
  • Take-home messages: S. Cayan
  • 12:30 - 13:00: Case 3. Is hormonal /adjuvant therapy useful prior to sperm retrieval procedure in infertile men with NOA?
  • Case presenter: S. Çayan
  • Pro: C. Konstantinidis
  • Cons: A. Bensouda
  • Take-home messages: G. Colpi
  • 13:00 - 14:00: LUNCH
  • 14:00 - 15:30: Surgical treatment of male infertility: Tips and tricks (Video session)
  • Moderators: A. Rambhatla, G.-M. Pinggera
  • 14:00 - 14:15: Microsurgical varicocele repair. S. Çayan
  • 14:15 - 14:30: Micro-TESE. G. Colpi
  • 14:30 - 14:45: Microsurgical vaso-epididymal anastomosis. R. Shah (by ZOOM)
  • 14:45 - 15:00: Endoscopic surgery of distal ejaculatory duct obstruction (TURED). S. Çayan
  • 15:00 - 15:30: Discussion
  • 15:30 - 16:00: COFFEE BREAK
  • 16:00 - 18:00: Managing an azoospermic couple: treatment protocols for the female and the male
  • 16:00 - 16:30: Gynecologist: Preparation of female and ovum retrieval for ART. C. Wyns
  • 16:30 - 17:00: Andrologist: Sperm retrieval in NOA - patient preparation, techniques, success rates, and predictors. A. Rambhatla
  • 17:00 - 17:30: Embryologist: Laboratory process: How to optimize sperm retrieval from mTESE samples? I. Maldonado
  • 17:30 - 18:00: Discussion
  • 18:00: CLOSING DAY 3

DAY 4 - DECEMBER 6, 2025

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